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Liver Disease

TELehealth EXercise for patients with primary liver cancer: TELEX-Liver Cancer

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Principal Investigator: Professor Helen Reeves

Strong evidence from randomised controlled trials supports structured exercise as an adjunctive therapy for patients with cancer. Unfortunately, for patients with hepatocellular carcinoma (HCC) –…

Understanding how bile acids cause cognitive deficits in Primary Biliary Cholangitis (PBC)

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Lucy Gee

This project aims to investigate the specific effects bile acids have on cell populations within the brain, as well as the ability of drug treatments to reverse these…

Lifestyle as Therapy in Liver Disease

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Jadine Scragg

This feasibility study aims to assess the proposed recruitment strategies in a well-defined patient group with advanced Non-alcoholic fatty liver disease (NAFLD) and will determine whether…

Personalised Nutrition in Non-Alcoholic Fatty Liver Disease (NAFLD): Feasibility of a Nutrigenomic Therapeutic Approach

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Laura Haigh 

NAFLD is a metabolic liver disease that poses a considerable challenge for 21st century healthcare. This increasingly common cause of liver dysfunction and multi-morbidity demands effective dietetic input…

Chronic Cognitive Impairment in Cholestatic Liver Disease: Impact, Pathogenesis, Treatment and Relevance to Dementia

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Principal Investigator: Professor David Jones

To develop the essential tools to allow us to explore the utility of early OCA as a transformative treatment for cholestatic cognitive impairment.

The Study

People normally…