Professor Jones previously led the Liver Disease research theme. He is Professor of Liver Immunology for the Faculty of Medical Science at Newcastle University. Additionally, he is Honorary Consultant Hepatologist with the Newcastle upon Tyne Hospitals NHS Foundation Trust. Dave also holds the position of NIHR Dean for Faculty Trainees, and is an NIHR Senior Investigator.

Dave has an international reputation for his work in autoimmune liver disease and leads the UK-PBC research consortium (MRC Stratified Medicine), which has the largest cohort of fully phenotyped primary biliary cholangitis/cirrhosis (PBC) patients. His areas of expertise are stratified therapeutics and symptom management.