Principal Investigator: Dr Gary Reynolds
There have been dramatic increases in life expectancy in the UK and these changes are predicted to continue with around 8.6 million people in 50…
MET-PREVENT is a Newcastle BRC-funded study. It will test whether the medicine metformin can…
Principal Investigator: Professor Ioakim Spyridopoulos
Up to 10% of symptomatic patients in the UK have been suffering from consequences related to COVID-19 for more than three months (‘long-COVID syndrome’). Up…
Principal Investigator: Professor Miles Witham
Recruiting people with multiple long-term conditions is essential if research studies are to be representative of people cared for by clinical services. Finding the right…
Principal Investigator: Mr Sandip Nandhra
Full title: A prospective multicentre observational study to determine the incidence of frailty, sarcopenia and multimorbidity in chronic limb threatening ischaemia and the associated impact…
Principal Investigator: Professor Miles Witham
The aim of the MET-PREVENT study is to determine whether the drug metformin, commonly used to treat diabetes, can improve physical function in older people…
Jamie Coulter
This research aims to allow the development of new therapeutics for orofacial pain patients.
Toothache is common, affecting up to 1 in 10 people in the UK and…
Samantha Waite
This research investigates sarcopenia and frailty in individuals with prodromal dementia with Lewy bodies and Alzheimer’s disease.
Sarcopenia and frailty are both increasingly recognised in older patients, but…
Nana-Jane Chipampe
This project aims to establish the suitability of measuring mitochondrial DNA (mtDNA) by sequencing Non-muscle Invasive Bladder Cancer patients’ urine.
Bladder cancer is the most common urinary tract…
Wezi Sendama
This project aims to test the hypothesis that ageing impairs the clearance of inflammatory cells such as neutrophils from the lung after their recruitment in acute inflammation. In…
Thomas Creasey
Genomic characterisation of acute lymphoblastic leukaemia in older adults
Acute lymphoblastic leukaemia (ALL) is the most frequent cancer of childhood but the disease also becomes more common with…
Stuart Maitland
Neurophysiology of age-related muscle weakness
As we grow old, we lose muscle bulk and strength. This muscle loss, termed ‘sarcopenia’, is a major burden on the health and…
