Principle Investigator: Professor Miles Witham
The aim of the MET-PREVENT study is to determine whether the drug metformin, commonly used to treat diabetes, can improve physical function in older people…
Jamie Coulter
This research aims to allow the development of new therapeutics for orofacial pain patients.
Toothache is common, affecting up to 1 in 10 people in the UK and…
Samantha Waite
This research investigates sarcopenia and frailty in individuals with prodromal dementia with Lewy bodies and Alzheimer’s disease.
Sarcopenia and frailty are both increasingly recognised in older patients, but…
Nana-Jane Chipampe
This project aims to establish the suitability of measuring mitochondrial DNA (mtDNA) by sequencing Non-muscle Invasive Bladder Cancer patients’ urine.
Bladder cancer is the most common urinary tract…
Wezi Sendama
This project aims to test the hypothesis that ageing impairs the clearance of inflammatory cells such as neutrophils from the lung after their recruitment in acute inflammation. In…
Thomas Creasey
Genomic characterisation of acute lymphoblastic leukaemia in older adults
Acute lymphoblastic leukaemia (ALL) is the most frequent cancer of childhood but the disease also becomes more common with…
Stuart Maitland
Neurophysiology of age-related muscle weakness
As we grow old, we lose muscle bulk and strength. This muscle loss, termed ‘sarcopenia’, is a major burden on the health and…
Matthew Birkbeck
Developing Magnetic Resonance Imaging (MRI) techniques to study functional muscle activity in ageing.
Sarcopenia is a condition affecting people over the age of 50 and is a progressive…
Leena Habiballa
With age, our muscle mass and strength decline, leading to loss of function and capacity for physical activity, known as…
Principal Investigator: Dr Richard Dodds
Establishing a life course cohort for advances in the prevention, diagnosis and treatment of sarcopenia.
Sarcopenia is the loss of muscle mass and function with…
Principal Investigator: Dr James Frith
This study aims to develop an efficacious and acceptable new therapy; ultimately aiming to improve the quality of life of older people with Orthostatic Hypotension…
Principal Investigator: Professor Avan Sayer
Two pilot studies (MASS-PD, recruiting patients with Parkinsons disease, and MASS pilot, a pilot study for the main MASS lifecourse study) have completed successfully. The…
