Skip to content

Ageing Syndromes

Five reasons to take part in research

Featured image 400795619

Each year, on 20th May we celebrate International Clinical Trials Day, as this is believed to be the date when the first ever clinical trial took place.

While the current…

Researchers support rehabilitation for older people after COVID-19

Featured image 841032209

Older people recovering from COVID-19 infection in Newcastle have received a boost to their rehabilitation, courtesy of researchers from the AGE Research Group (Ageing, Geriatrics & Epidemiology) at Newcastle…

NIHR Newcastle BRC’s response to national COVID-19 crisis

Featured image 1269560829

Scientists and clinicians working as part of the NIHR Newcastle Biomedical Research Centre (BRC) share what they are doing in support of the unprecedented challenges during COVID-19

As part…

STOP-TRANSIT study: Peri-procedural targets in toothache to stop transition to phantom neuropathic tooth pain

Featured image 821610519

Jamie Coulter

This research aims to allow the development of new therapeutics for orofacial pain patients.

The Study

Toothache is common, affecting up to 1 in 10 people in the UK and…

Sarcopenia and Frailty in early dementia with Lewy bodies

Featured image 83304598

Samantha Waite

This research investigates sarcopenia and frailty in individuals with prodromal dementia with Lewy bodies and Alzheimer’s disease.

The Study

Sarcopenia and frailty are both increasingly recognised in older patients, but…

Age-related bladder dysfunction and mitochondrial biology

Featured image 2061135453

Nana-Jane Chipampe

This project aims to establish the suitability of measuring mitochondrial DNA (mtDNA) by sequencing Non-muscle Invasive Bladder Cancer patients’ urine.

The Study

Bladder cancer is the most common urinary tract…

Multiple long-term conditions (or multimorbidity) – what is it and why is it an issue?

Featured image 1735828996

Miles Witham is Professor of Trials for Older People at Newcastle University, and the Ageing Syndromes Deputy Theme Lead with the Newcastle Biomedical Research Centre.

The effect of ageing on the resolution of inflammation

Featured image 1464187351

Wezi Sendama

This project aims to test the hypothesis that ageing impairs the clearance of inflammatory cells such as neutrophils from the lung after their recruitment in acute inflammation. In…

Unravelling the mutational landscape of acute lymphoblastic leukaemia in older adults to improve treatment.

Featured image 1268646189

Thomas Creasey

Genomic characterisation of acute lymphoblastic leukaemia in older adults

The Study

Acute lymphoblastic leukaemia (ALL) is the most frequent cancer of childhood but the disease also becomes more common with…

Developing novel biomarkers of motor system changes in ageing humans.

Featured image 302266932

Stuart Maitland

Neurophysiology of age-related muscle weakness

The Study

As we grow old, we lose muscle bulk and strength. This muscle loss, termed ‘sarcopenia’, is a major burden on the health and…

Development of a novel imaging method “Motor Unit Magnetic Resonance Imaging” (MUMRI) to investigate motor unit activity in ageing.

Featured image 166336268

Matthew Birkbeck

Developing Magnetic Resonance Imaging (MRI) techniques to study functional muscle activity in ageing.

The Study

Sarcopenia is a condition affecting people over the age of 50 and is a progressive…

Investigating the impact of cellular senescence on muscle ageing

Featured image 1449351871

Leena Habiballa

With age, our muscle mass and strength decline, leading to loss of function and capacity for physical activity, known as…