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Dementia Projects

CamEL Project – improving the diagnosis of early Lewy body disease

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Principal Investigator: Dr Gemma Roberts

Full title: Improving the Interpretation of Cardiac Sympathetic Imaging with MIBG for More Accurate Diagnosis of Early Lewy Body Disease

Did you know that a heart…

“ESP+” – Extending and Improving ESP in the Diagnosis of Dementia with Lewy Bodies and Parkinson’s Disease

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Principal Investigator: Dr Lina Gliaudelytė

Image: Fibrils of alpha-synuclein produced using ESP

Each year in the UK there are around 20,000 new cases of dementia with Lewy bodies (DLB) and 20,000…

Using EEG to understand and identify delirium in inpatients with Parkinson’s disease

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Principal Investigator: Dr Rachael Lawson

Research has shown that people with Parkinson’s disease (PD) are at increased risk of delirium. Delirium is an acute neuropsychiatric syndrome associated with altered levels…

Networks and genes: towards a better understanding of cholinergic dysfunction in Lewy body dementia

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Principal Investigator: Dr Jude Harrison

Lewy body dementia (LBD), which includes Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB), is characterised by significant damage to key brain networks,…

Developing novel tools to accurately identify dementia subtypes: application of wearable based gait analysis and machine learning approaches

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Principal Investigator: Rana Zia Ur Rehman

Many different subtypes of dementia have similarities in clinical presentation, but a more accurate diagnosis is important to allow individuals to understand and manage…

Understanding how local area deprivation, health inequality and multimorbidity contribute to progression of dementia and cognitive impairment

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Principal Investigator: Dr Calum Hamilton

The Study

As many as 40% of dementia cases may be preventable through addressing modifiable individual risk factors in earlier life. However, many of these factors…

Sarcopenia and Frailty in early dementia with Lewy bodies

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Samantha Waite

This research investigates sarcopenia and frailty in individuals with prodromal dementia with Lewy bodies and Alzheimer’s disease.

The Study

Sarcopenia and frailty are both increasingly recognised in older patients, but…

Brain dynamics as confirmatory biomarker of dementia with Lewy bodies versus Alzheimer’s disease – An electrophysiological study

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Ramtin Mehraram

This research focuses on assessing how the electrical activity of the brain is affected in the different forms of dementia. With this research he aims to contribute in…