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Liver Disease

Series of films on fatigue, available to the public

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Experts across healthcare and academia in Newcastle have produced a number of short patient education films aimed at supporting people with symptoms of fatigue as they recover from COVID-19.

The…

Welcoming another trainee to the Newcastle BRC

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At the NIHR Newcastle BRC, providing an inspirational environment for career development is something we are passionate about. The latest trainee to come on board is Colette Kirk, a…

Understanding how bile acids cause cognitive deficits in Primary Biliary Cholangitis (PBC)

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Lucy Gee

This project aims to investigate the specific effects bile acids have on cell populations within the brain, as well as the ability of drug treatments to reverse these…

Lifestyle as Therapy in Liver Disease

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Jadine Scragg

This feasibility study aims to assess the proposed recruitment strategies in a well-defined patient group with advanced NAFLD and will determine whether an 8-week very vLCD is an…

Personalised Nutrition in Non-Alcoholic Fatty Liver Disease (NAFLD): Feasibility of a Nutrigenomic Therapeutic Approach

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Laura Haigh 

NAFLD is a metabolic liver disease that poses a considerable challenge for 21st century healthcare. This increasingly common cause of liver dysfunction and multi-morbidity demands effective dietetic input…

Stratified medicine in Primary Biliary Cholangitis

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Liver disease research in Newcastle has identified areas of unmet need in PBC; in particular, sub-optimal response to established therapies.

Primary Biliary Cholangitis (PBC) is a chronic liver disease affecting…

Chronic Cognitive Impairment in Cholestatic Liver Disease: Impact, Pathogenesis, Treatment and Relevance to Dementia

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Principal Investigator: Professor David Jones

To develop the essential tools to allow us to explore the utility of early OCA as a transformative treatment for cholestatic cognitive impairment.

The Study

People normally…

NIHR Award supports physiotherapist Kate Hallsworth’s research career

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Dr Kate Hallsworth, a Senior Research Physiotherapist and NIHR Clinical Lecturer at The Newcastle upon Tyne Hospitals NHS Foundation Trust/Newcastle University and joint Principal Investigator on a project co-funded…