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Skin and Oral Disease

STOP-TRANSIT study: Peri-procedural targets in toothache to stop transition to phantom neuropathic tooth pain

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Jamie Coulter

This research aims to allow the development of new therapeutics for orofacial pain patients.

The Study

Toothache is common, affecting up to 1 in 10 people in the UK and…

Interrogating mitochondrial dysfunction in human facial appearance and ageing

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Roisin Stout

The main objective of this project is to investigate the role of mitochondrial dysfunction in ageing- specifically in relation to the skin.

The Study

Mitochondria are the batteries of the…

Innovative data mining using deep learning advanced photoplethysmography pulse wave analysis

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Sadaf Iqbal

Full title: Innovative data mining using deep learning advanced photoplethysmography pulse wave analysis for the assessment of endothelial dysfunction in systemic sclerosis and related cardiovascular conditions.

This project focuses…

An investigation of the credentials of a novel lysine deacetylase as an age-related biomarker for periodontitis

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Christopher Dowson 

The aim of the project is to investigate the role of SIRT2 in periodontitis in cell culture models in vitro and as a diagnostic measure in vivo.

The Study

Periodontitis…

Investigating the role of Langhans type multinucleated giant cells in giant cell arteritis.

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Daniel Maunder 

The aim of this project is to investigate the formation & function of Langhans-type multinucleated giant cells to improve our understanding of giant cell arteritis.

The Study

Giant cell arteritis…

Newcastle BRC’s Professor Muzlifah Haniffa part of team to develop first cell atlas of human thymus gland

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Professor Muzlifah Haniffa, NIHR Newcastle BRC Skin & Oral Disease Theme Lead, alongside researchers from the Wellcome Sanger Institute, Newcastle University and Ghent University, Belgium, has helped to…

Scratching the surface: Gene signatures in pigmented skin lesions

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Principal Investigator: Dr Neil Rajan

This project aims to support research that underpins the understanding of skin cancer in the elderly population by exploring how gene signatures in melanomas vary…

Muzlifah Haniffa – Nature Medicine career perspective

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Professor Muzlifah Haniffa has been featured in a Nature Medicine career perspective
Publication: Nature Medicine
Title: Muzlifah Haniffa—a new era for collaborative and supportive medical research
Date published: 11 February 2020
Link:

Functional and single-cell genomic characterisation of atopic dermatitis endotypes

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Principal Investigators: Professor Muzlifah Haniffa and Professor Nick J Reynolds

We are combining pioneering single cell sequencing technology with our clinical expertise and well characterised cohorts of atopic dermatitis (eczema)…

Professor Muzz Haniffa wins prestigious award

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Professor Muzlifah Haniffa, Theme Lead for the NIHR Newcastle BRC Skin & Oral Disease area, has won the 2019 Foulkes Foundation Medal, awarded to a rising star making a…