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Liver disease, multimorbidity and lifestyle

Chronic liver disease is a major cause of poor quality of life and is a contributor to excess death, making it a significant concern for both patients and the NHS.

In our liver disease theme, we explore the contribution that the ageing process makes to the biology of liver disease. To do this, we harness the expertise of Newcastle’s world-class ageing biology research.

Theme co-leads are; Quentin Anstee, Professor of Experimental Hepatology and an Honorary Consultant Hepatologist at Newcastle Hospitals. He leads one of the largest NAFLD clinical services in the UK.

And Professor Helen Reeves, an academic hepatologist, looking after patients with primary liver cancer.

What we cover in this theme

Newcastle BRC’s Liver Disease Theme studies the following conditions:

  • Primary Biliary Cholangitis (PBC)
  • Non alcoholic fatty liver disease (NAFLD)
  • Auto immune hepatitis (AIH)

We are researching the mechanisms behind these conditions in order to find treatments that can improve the quality of life for those diagnosed.


Professor Quentin M Anstee

Co-theme lead for Liver Disease, Multimorbidity and Lifestyle

Professor Helen Reeves

Co-theme lead for Liver Disease, Multimorbidity and Lifestyle

Professor Derek Mann

Professor of Hepatology

Professor Alastair Burt

Theme lead for Informatics and Precision Care for an Ageing Population

Dr Chris Lamb

Emerging leader for Liver Disease, Multimorbidity and Lifestyle theme

Dr Kate Hallsworth

Development Skills Enhancement Awardee

Dr Sam Orange

Lecturer in exercise physiology